LU85544A1 - Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique - Google Patents
Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique Download PDFInfo
- Publication number
- LU85544A1 LU85544A1 LU85544A LU85544A LU85544A1 LU 85544 A1 LU85544 A1 LU 85544A1 LU 85544 A LU85544 A LU 85544A LU 85544 A LU85544 A LU 85544A LU 85544 A1 LU85544 A1 LU 85544A1
- Authority
- LU
- Luxembourg
- Prior art keywords
- radical
- methyl
- tert
- tetrahydro
- naphthyl
- Prior art date
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- 239000002537 cosmetic Substances 0.000 title claims description 10
- 238000002360 preparation method Methods 0.000 title description 3
- 230000001225 therapeutic effect Effects 0.000 title 1
- -1 2-oxazolinyl radical Chemical class 0.000 claims description 118
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- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 30
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 27
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- 229910052757 nitrogen Inorganic materials 0.000 claims description 12
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- 125000000623 heterocyclic group Chemical group 0.000 claims description 8
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- 125000004093 cyano group Chemical group *C#N 0.000 claims description 2
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- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 2
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- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 claims description 2
- 125000003107 substituted aryl group Chemical group 0.000 claims description 2
- 125000001302 tertiary amino group Chemical group 0.000 claims description 2
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- 125000004429 atom Chemical group 0.000 claims 2
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- 229960001727 tretinoin Drugs 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (35)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU85544A LU85544A1 (fr) | 1984-09-19 | 1984-09-19 | Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique |
SE8504291A SE461466B (sv) | 1984-09-19 | 1985-09-16 | Aromatiska heterocykliska derivat och deras anvaendning inom det terapeutiska och kosmetiska omraadet |
PT81132A PT81132B (pt) | 1984-09-19 | 1985-09-16 | Processo para a preparacao de novos compostos heterociclicos aromaticos derivados do acido 2-(p-terc-butilfenil) carboxilico designados por "hetero-diferinas", aplicaveis em terapeutica humana ou veterinaria e em cosmetica |
FR8513747A FR2570377B1 (fr) | 1984-09-19 | 1985-09-17 | Derives heterocycliques aromatiques et leur application dans les domaines therapeutique et cosmetique |
AR85301653A AR243504A1 (es) | 1984-09-19 | 1985-09-18 | Procedimiento de preparacion de compuestos heterociclicos de benzofurano, benzotiofeno, indol, benzoxazol, benzotiazol y benzimidazol. |
CH4050/85A CH665841A5 (fr) | 1984-09-19 | 1985-09-18 | Derives heterocycliques aromatiques et compositions therapeutiques et cosmetiques les contenant. |
AT0271885A AT395714B (de) | 1984-09-19 | 1985-09-18 | Verfahren zur herstellung von neuen aromatischen heterocyclischen verbindungen |
IT8522180A IT1209663B (it) | 1984-09-19 | 1985-09-18 | Derivati eterociclici aromatici eloro applicazione nei settori terapeutico e cosmetico. |
JP60207724A JPH0784437B2 (ja) | 1984-09-19 | 1985-09-18 | 複素環レチノイド |
DE3533308A DE3533308C2 (de) | 1984-09-19 | 1985-09-18 | Aromatische, heterocyclische Derivate und ihre Verwendung auf dem pharmazeutischen und kosmetischen Gebiet |
NL8502557A NL192878C (nl) | 1984-09-19 | 1985-09-18 | Aromatische heterocyclische verbindingen en farmaceutische en cosmetische preparaten die deze bevatten. |
CH965/88A CH675241A5 (en]) | 1984-09-19 | 1985-09-18 | |
CA000491026A CA1256804A (fr) | 1984-09-19 | 1985-09-18 | Compositions pharmaceutiques contenant a titre de principe actif un ou plusieurs derives heterocycliques aromatiques |
AU47559/85A AU578310B2 (en) | 1984-09-19 | 1985-09-18 | Therapeutic and cosmetic heteroaromatic compounds |
CA000491024A CA1256862A (fr) | 1984-09-19 | 1985-09-18 | Derives heterocycliques aromatiques et leur procede de preparation |
GR852270A GR852270B (en]) | 1984-09-19 | 1985-09-18 | |
ES547750A ES8608487A1 (es) | 1984-09-19 | 1985-09-18 | Procedimiento de preparar compuestos heterociclicos aromati-cos |
ZA857158A ZA857158B (en) | 1984-09-19 | 1985-09-18 | Aromatic heterocyclic derivatives and their application in the therapeutic and cosmetic fields |
BE0/215596A BE903254A (fr) | 1984-09-19 | 1985-09-18 | Derives heterocycliques aromatiques et leur application dans les domaines therapeutique et cosmetique |
DK423285A DK169475B1 (da) | 1984-09-19 | 1985-09-18 | Heterocycliske aromatiske forbindelser og farmaceutiske og kosmetiske præparater deraf |
DE3546907A DE3546907C2 (de) | 1984-09-19 | 1985-09-18 | Aromatische, heterocyclische Verbindungen sowie diese Verbindungen enthaltende pharmazeutische und kosmetische Zubereitungen und Arzneimittel |
GB8523203A GB2164648B (en) | 1984-09-19 | 1985-09-19 | Aromatic heterocyclic derivatives and their application in the therapeutic and cosmetic fields |
MX009009A MX166783B (es) | 1984-09-19 | 1985-10-01 | Procedimiento de preparacion de compuestos heterociclicos aromaticos |
US06/839,269 US4740519A (en) | 1984-09-19 | 1986-03-13 | Benzo (b) thiophene carboxylate derivatives and pharmaceutical compositions |
BE0/216415A BE904421A (fr) | 1984-09-19 | 1986-03-14 | Derives heterocycliques aromatiques et leur application dans les domaines therapeutique et cosmetique. |
AU62995/86A AU593838B2 (en) | 1984-09-19 | 1986-09-22 | 4-Hydroxy/alkoxy benzoic acid derivatives |
GB878722903A GB8722903D0 (en) | 1984-09-19 | 1987-09-30 | Aromatic heterocyclic derivatives |
GB8727803A GB2197320B (en) | 1984-09-19 | 1987-11-27 | Intermediates useful in the preparation of therapeutic and cosmetic aromatic heterocylic derivatives |
SE8800949A SE502470C2 (sv) | 1984-09-19 | 1988-03-16 | Aromatiska karboxylsyraderivat och användning av dessa som mellanprodukter |
US07/172,494 US4920140A (en) | 1984-09-19 | 1988-03-24 | Benzimidazole derivatives and their thereapeutic and cosmetic use |
US07/430,286 US5059621A (en) | 1984-09-19 | 1989-11-02 | Aromatic heterocyclic derivatives and their thereapeutic and cosmetic use |
US07/696,708 US5260295A (en) | 1984-09-19 | 1991-05-07 | Aromatic heterocyclic derivatives and their therapeutic and cosmetic use |
AT0042192A AT401514B (de) | 1984-09-19 | 1992-03-05 | Verfahren zur herstellung von neuen organischen säuren bzw. säurechloriden |
US07/900,479 US5288744A (en) | 1984-09-19 | 1992-06-18 | Aromatic heterocyclic derivatives and their therapeutic and cosmetic use |
US08/160,225 US5428052A (en) | 1984-09-19 | 1993-12-02 | Aromatic heterocyclic derivatives and their therapeutic and cosmetic use |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU85544A LU85544A1 (fr) | 1984-09-19 | 1984-09-19 | Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique |
LU85544 | 1984-09-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
LU85544A1 true LU85544A1 (fr) | 1986-04-03 |
Family
ID=19730321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LU85544A LU85544A1 (fr) | 1984-09-19 | 1984-09-19 | Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique |
Country Status (21)
Country | Link |
---|---|
US (3) | US4740519A (en]) |
JP (1) | JPH0784437B2 (en]) |
AR (1) | AR243504A1 (en]) |
AT (2) | AT395714B (en]) |
AU (2) | AU578310B2 (en]) |
BE (2) | BE903254A (en]) |
CA (2) | CA1256804A (en]) |
CH (2) | CH665841A5 (en]) |
DE (2) | DE3546907C2 (en]) |
DK (1) | DK169475B1 (en]) |
ES (1) | ES8608487A1 (en]) |
FR (1) | FR2570377B1 (en]) |
GB (3) | GB2164648B (en]) |
GR (1) | GR852270B (en]) |
IT (1) | IT1209663B (en]) |
LU (1) | LU85544A1 (en]) |
MX (1) | MX166783B (en]) |
NL (1) | NL192878C (en]) |
PT (1) | PT81132B (en]) |
SE (2) | SE461466B (en]) |
ZA (1) | ZA857158B (en]) |
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US4448006A (en) | 1981-05-28 | 1984-05-15 | Donn Incorporated | Grid ceiling structure and method of converting |
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FR2603280B1 (fr) * | 1986-08-29 | 1988-10-28 | Cird | Nouveau compose marque au tritium, sa preparation et son application notamment dans la determination de l'affinite des retinoides pour leur recepteur cellulaire |
NZ223237A (en) * | 1987-01-22 | 1991-03-26 | Shiseido Co Ltd | Hair growth promoting agent and compositions |
US5149705A (en) * | 1987-03-13 | 1992-09-22 | Allergan, Inc. | Acetylenes disubstituted with a heteroaromatic group and a tetralin group and having retinoid like activity |
US5602130A (en) * | 1987-03-20 | 1997-02-11 | Allergan | Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity |
US5264578A (en) * | 1987-03-20 | 1993-11-23 | Allergan, Inc. | Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity |
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FR2614618B1 (fr) * | 1987-04-30 | 1989-07-07 | Cird | Derives heterocycliques polycycliques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire |
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US5366986A (en) * | 1988-04-15 | 1994-11-22 | T Cell Sciences, Inc. | Compounds which inhibit complement and/or suppress immune activity |
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DE3830054A1 (de) * | 1988-09-03 | 1990-03-15 | Boehringer Mannheim Gmbh | Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
US5166170A (en) * | 1989-07-03 | 1992-11-24 | Hoechst-Roussel Pharmaceuticals Incorporated | 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders |
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- 1985-09-19 GB GB8523203A patent/GB2164648B/en not_active Expired
- 1985-10-01 MX MX009009A patent/MX166783B/es unknown
-
1986
- 1986-03-13 US US06/839,269 patent/US4740519A/en not_active Expired - Lifetime
- 1986-03-14 BE BE0/216415A patent/BE904421A/fr not_active IP Right Cessation
- 1986-09-22 AU AU62995/86A patent/AU593838B2/en not_active Expired
-
1987
- 1987-09-30 GB GB878722903A patent/GB8722903D0/en active Pending
- 1987-11-27 GB GB8727803A patent/GB2197320B/en not_active Expired
-
1988
- 1988-03-16 SE SE8800949A patent/SE502470C2/sv not_active IP Right Cessation
- 1988-03-24 US US07/172,494 patent/US4920140A/en not_active Expired - Lifetime
-
1989
- 1989-11-02 US US07/430,286 patent/US5059621A/en not_active Expired - Lifetime
-
1992
- 1992-03-05 AT AT0042192A patent/AT401514B/de not_active IP Right Cessation
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